Hereditary causes of kidney tumours
نویسندگان
چکیده
منابع مشابه
Hereditary Tumours
Hereditary tumours account for 3–10% of all cancers. Greater susceptibility of the subjects to these types of malignancies is thought to be the result of genetic mutations in highly penetrant genes transmitted as autosomal dominant traits. Mutations in such susceptibility genes result in familial predisposition to developing a characteristic spectrum of diseases (collectively known as Hereditar...
متن کاملKidney Tumours
Introduction A variety of benign and malignant tumours can arise in the kidney in children. With minor variations, the spectrum of tumours has worldwide distribution. Wilms’ tumour (WT; also known as nephroblastoma) is the most common kidney tumour in childhood, and may represent the most common abdominal tumour presenting in infants and children in sub-Saharan Africa. In the past decade, consi...
متن کاملMalignant Tumours of the Kidney
was first established by Robin in 1855. Later, yellow coloured tumours of small or large size, well circumscribed, vascular, liable to haemorrhages, degeneration and cyst formation were noticed in the region of the kidney, which led pathologists to speculate concerning their origin. At first they were thought to be lipomatous in structure until Grawitz in 1883 thought that the structure was ide...
متن کامل5. Hereditary Kidney Disorders
Hereditary kidney disorders represent significant risk for the development of end stage renal desease (ESRD). Most of them are recognized in childhood, or prenataly particularly those phenotypicaly expressed as anomalies on ultrasound examination (US) during pregnancy. They represent almost 50% of all fetal malformations detected by US (1). Furthermore many of urinary tract malformations are as...
متن کاملEnvironmental causes of childhood brain tumours.
Brain tumours hitherto said to be rare in Africans are now known to be common. They cause considerable concern due to their relatively high morbidity, mortality and enormous cost of care, especially in the developing world. An understanding of the aetiology is particularly important in our region for planning strategies for effective prevention of brain tumours. This review endeavours to outlin...
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ژورنال
عنوان ژورنال: European Journal of Clinical Investigation
سال: 2010
ISSN: 0014-2972,1365-2362
DOI: 10.1111/j.1365-2362.2010.02270.x